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Michael Bubser Selected Research

VU0467485

2/2017Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia.

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Michael Bubser Research Topics

Disease

13Schizophrenia (Dementia Praecox)
11/2020 - 02/2005
8Parkinson Disease (Parkinson's Disease)
01/2017 - 07/2009
5Alzheimer Disease (Alzheimer's Disease)
12/2020 - 10/2008
5Catalepsy
01/2016 - 10/2008
2Opioid-Related Disorders (Opiate Addiction)
01/2022 - 01/2019
2Pain (Aches)
05/2019 - 01/2019
2Neurobehavioral Manifestations
01/2018 - 01/2012
2Dyskinesias (Dyskinesia)
01/2016 - 08/2015
2Parkinsonian Disorders (Parkinsonism)
03/2012 - 07/2009
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2020
1Substance-Related Disorders (Drug Abuse)
03/2016
1Cocaine-Related Disorders (Cocaine Addiction)
03/2016
1Fragile X Syndrome (Martin Bell Syndrome)
01/2016
1Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
03/2015
1Psychotic Disorders (Schizoaffective Disorder)
06/2014
1Nerve Degeneration
03/2012
1Nervous System Diseases (Neurological Disorders)
01/2012
1Angelman Syndrome (Syndrome, Angelman)
09/2010
1MPTP Poisoning
07/2009
1Body Weight (Weight, Body)
08/2002
1Weight Gain
08/2002
1Weight Loss (Weight Reduction)
08/2002

Drug/Important Bio-Agent (IBA)

8Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2022 - 10/2008
4Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
01/2016 - 02/2012
4Haloperidol (Haldol)FDA LinkGeneric
01/2016 - 02/2012
4Antipsychotic Agents (Antipsychotics)IBA
01/2012 - 08/2002
3N-Methylaspartate (NMDA)IBA
12/2016 - 05/2015
3Glutamate Receptors (Glutamate Receptor)IBA
12/2016 - 05/2015
3Levodopa (L Dopa)FDA LinkGeneric
01/2016 - 02/2012
3Dopamine (Intropin)FDA LinkGeneric
03/2012 - 02/2005
2Cholinergic Agents (Cholinergics)IBA
12/2020 - 01/2012
2Morphine (MS Contin)FDA LinkGeneric
05/2019 - 01/2019
2VU0466551IBA
05/2019 - 01/2019
2Analgesics (Analgesic Drugs)IBA
05/2019 - 01/2019
2Opioid Analgesics (Opioids)IBA
01/2019 - 01/2019
2Dizocilpine Maleate (Dizocilpine)IBA
01/2018 - 03/2016
2Clozapine (Clozaril)FDA LinkGeneric
03/2016 - 08/2002
2metabotropic glutamate receptor 4IBA
01/2016 - 08/2015
2N-(3-chlorophenyl)picolinamideIBA
08/2015 - 02/2012
2Serotonin (5 Hydroxytryptamine)IBA
03/2015 - 07/2009
2Oxidopamine (6 Hydroxydopamine)IBA
03/2012 - 02/2012
2OrexinsIBA
11/2007 - 08/2002
1VU6019650IBA
01/2022
1Opioid Receptors (Opioid Receptor)IBA
01/2019
1VU0467485IBA
02/2017
1VU0476406IBA
01/2017
1Hypnotics and Sedatives (Sedatives)IBA
03/2016
15- amino- 3,4- dimethyl- N- (4- ((trifluoromethyl)sulfonyl)benzyl)thieno(2,3- c)pyridazine- 6- carboxamideIBA
03/2016
1Metabotropic Glutamate 5 ReceptorIBA
03/2016
1Therapeutic UsesIBA
01/2016
1gamma-Aminobutyric Acid (GABA)IBA
08/2015
1LSP1 2111IBA
08/2015
1Dihydroxyphenylalanine (Dopa)IBA
08/2015
1Glutamic Acid (Glutamate)FDA Link
08/2015
1Neurotransmitter Agents (Neurotransmitter)IBA
03/2015
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
03/2015
1Neuropeptide YIBA
03/2015
1SaltsIBA
03/2013
1metabotropic glutamate receptor 8IBA
03/2013
1Reserpine (Serpasil)FDA Link
03/2013
12- (2- furanyl)- 7- (2- (4- (4- (2- methoxyethoxy)phenyl)- 1- piperazinyl)ethyl)- 7H- pyrazolo(4,3- e)(1,2,4)triazolo(1,5- c)pyrimidine- 5- amineIBA
02/2012
1Adenosine (Adenocard)FDA LinkGeneric
02/2012
1Cholinergic ReceptorsIBA
01/2012
1Muscarinic AgonistsIBA
01/2012
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2012
1Cholinesterase Inhibitors (Anticholinesterases)IBA
01/2012
1Acetylcholine (Acetylcholine Chloride)FDA Link
01/2012
1Proteins (Proteins, Gene)FDA Link
09/2010
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
09/2010
1Norepinephrine (Noradrenaline)FDA LinkGeneric
07/2009
1NeurotensinIBA
02/2005
1Peptides (Polypeptides)IBA
08/2002
1Amphetamine (Amfetamine)FDA LinkGeneric
08/2002

Therapy/Procedure

1Drug Therapy (Chemotherapy)
03/2016
1Denervation
07/2009